Science is just beginning to study
and understand the world of bacteria within our bodies. There are trillions of
bugs inside each human, and these bugs can be “good” (beneficial) or “bad”
(pathogenic, or disease-causing). Essentially, the human body is a donut, with
a hole in the middle that goes from your mouth to your anus. The bacteria and
food in the donut hole are not technically “in” our bodies, until they are actively
absorbed by our bodies through the enterocytes (intestinal cells). With ten times more bugs than cells in our bodies, it’s almost more like they are the vehicle
for humans rather than us being the vehicle for them.
Another, more harmful way that food
and bacteria make it from the intestines into our blood stream is through tiny holes between the
enterocytes. These tiny holes are called loose junctions, or “leaky gut”. Some researchers
claim that up to 90% of people in the West have some amount of leaky gut, which
is caused by a range of things like gluten (a protein found in grains like
wheat), antibiotics, yeast overgrowth, eating a high-sugar diet, pharmaceutical medications, NSAIDS
(ibuprofen or Advil), alcoholism, and drug use.
Two problems appear when our
enterocytes are damaged and become leaky. First of all, food and bacteria from
our gut leaks into the blood stream and the body responds with an immune
attack. It not only attacks the invading bacteria, but also sees intact
proteins (long strings of amino acids) from our food leaking into the blood stream, rather than the single amino acids that
are normally absorbed through the intestinal cells. The body also “thinks”
these are bacteria (especially gluten and casein from dairy) and attacks them
as well. Over long periods of time, these heightened immune responses wreck
havoc on the body and likely contribute or cause the development of autoimmune
diseases like type I diabetes, rheumatoid arthritis, psoriasis, lupus, celiac, and
multiple sclerosis.
The second way that damaged
enterocytes further cause problems in the body is due to their inability to
digest food properly. Instead of the food being broken up right away by enzymes
(made by the enterocytes), the food sits in the gut and putrifies. This rotting
food overwhelmingly feeds the pathogenic bacteria, especially the high carbohydrate,
high sugar diets that are common in the West. When there is an imbalance in
bacteria in the gut, it is referred to as “gut dysbiosis” and has been
associated with inflammatory bowel disease, colitis, chronic fatigue syndrome,
and cancer. For many people, the feeding of pathogenic bacteria also leads to bloating, belching, acid reflux, and constipation/diarrhea .
Not only are high numbers of
pathogenic species thought to contribute to autoimmune disease and the diseases
of gut dysbiosis, but they also cause inflammation and links are being made to
chronic diseases as well like heart disease, type II diabetes, and obesity. The
links to obesity are especially fascinating. A study from Washington
University, published in the elite journal Science, showed that specific
bacterial species are correlated with either obesity or thinness. Previous studies have found that obese people and thin people often have very different strains of intestinal bacteria. In this study, they inoculated germ-free mice (grown in a sterile environment) with
bacteria from human twins, one of which was obese and one of which was thin.
The mice receiving bugs from the obese twin gained statistically significant
more weight than the mice given bugs from the thin twin, despite being fed the
same chow. Although there is still much to be studied and learned about bacteria,
studies like this show that it is a very promising topic in the field of
obesity research.
Although much nutrition advice in
this field has centered around adding probiotics like acidophilus to the diet,
recent research has shown fermented foods (yogurt, kimchi, raw sauerkraut, and
kombucha) and prebiotics to be even more effective at inoculating the digestive
tract with beneficial species and healing disease. Feeding our existing beneficial
bacteria with PREbiotics - like inulin, FOS (fructo-oligo saccharides), and
resistant starch are thought by some to be even more effective than adding in
new species. Coconut products and bone broth have also been found to be
effective at healing leaky gut and helping beneficial species to thrive.
Another common gut problem that
causes discomfort for many people is SIBO – small intestinal bacterial
overgrowth. This is caused by an overgrowth of pathogenic species in the small
intestine, rather than the beneficial bugs being concentrated in the large
intestine, or colon, like they are in a healthy person. When numbers in the small intestine are closer to 104
rather than 103, which is normal, this can cause also symptoms like
bloating, belching, acid reflux, stomach distention and pain.
There are a few different diets
that are recommended for autoimmune diseases as well as other diseases
associated with gut dysbiosis. One that has become very popular and effective
for many is the SCD – specific carbohydrate diet. This diet recommends limiting
carbohydrates that are made of two or more sugar molecules linked together
(sucrose, maple syrup, and starches from things like potatoes and flour) based
on the idea that damaged enterocytes are unable to produce the necessary
enzymes to break them down and they feed the harmful bacteria. Carbohydrates
made of single sugars like fruit and honey are allowed, since they don't require enzymes to be digested and so don’t feed the harmful bacteria but instead are
absorbed quickly and used for energy by the body. People who suffer from
bloating and gut-related discomfort like gas, belching, and
constipation/diarrhea often find relief from this diet. Some believe that after
a healing period, problematic foods can be added back into the diet without
causing symptoms.
Another similar diet that is growing in popularity is the GAPS diet. This stands for Gut and Psychology Syndrome and was designed by Dr. Natasha Campbell-McBride. Her book by the same name details the relationship of high number of pathogenic bacteria and their relationship to issues of mental illness, including depression, anxiety, bi-polar disorder, the autism/Asperger's spectrum, and more. Her theory, which is fascinating and has shown correlation in a number of scientific studies, is that pathogenic bacteria emit neurotoxins which pass the blood-brain barrier and cause mental illness. This also explains the exponential increase in depression and mental illness we've seen in Western countries in the last century. She also discusses a phenomenon she calls "glue ear," which is the idea that reoccuring ear infections (otitis media) in children are caused by pathogenic bacteria making their way into the inner ear through the opening into the throat and causing mucus and infection in the middle ear. Her dietary advice is very similar to the SCD and excludes starch and double sugars as well as a gut-healing protocol including lots of bone broth. Many families report success treating depression and autism spectrum disorders in children using this approach.
There is variation of the SCD used in some circumstances is the low-FODMAP diet, which excludes foods containing even small amounts of short chain carbohydrates that are highly fermentable and poorly absorbed in the small intestine, including sugar alcohols, certain vegetables and fruits, grains, and some of the aforementioned prebiotics.
There is variation of the SCD used in some circumstances is the low-FODMAP diet, which excludes foods containing even small amounts of short chain carbohydrates that are highly fermentable and poorly absorbed in the small intestine, including sugar alcohols, certain vegetables and fruits, grains, and some of the aforementioned prebiotics.
There are a number of supplements
that are useful in removing the pathogenic bacteria and helping the beneficial
bugs to take hold, as well as lowering the numbers of the harmful species
present with SIBO. Often the harmful bugs include yeasts like Candida Albicans,
which are able to take hold after the administration of antibiotics which kill
off multiple species of good and bad bacteria and allow yeasts to take over.
The yeasts and other harmful bugs create a home for themselves called a
“biofilm” that makes it hard for beneficial bugs to kick them out. A commonly
known biofilm is the plaque on our teeth, and one can think of biofilms as a
plaque that covers the intestinal lining. There are a number of biofilm
disruptors on the market that can be useful, as well as herbal versions like
grapefruit seed extract and coconut oil.
Although definitely a strange
concept at first, the medical treatment recently discovered that has shown the
best results is the fecal transplant. Like it sounds, this involves taking the
feces or isolated bacteria from the feces of a healthy person and injecting it
or orally delivering it into the colon of the unhealthy person. For diseases
with high mortality like Clostridium difficile, it has shown to be
astonishingly effective. Although in its infancy, methods like this will likely
be explored as a cure for a growing number of diseases and ailments.
Lastly, a group of researchers
created the Human Food Project and are now conducting a study called American
Gut, looking into the variety and specific species present in different
Americans. For $99 (or less for 2 or more people’s samples) they send you a
home kit to mail them a feces sample. They then send you a list of your
bacteria species and their relative abundance in your gut, as well as on your
skin and in your mouth, and compare this to other Americans (including famous
author Michael Pollan) as well as a primitive tribe that they have been
studying.
This very exciting field of science
holds a lot of promise for people suffering from this long list of gut-related,
auto-immune, and chronic diseases. There is much to learn but from what we
already know, dietary changes and some simple supplements can be even more
effective than any of the medications that western medicine now prescribes –
which often only treat the symptoms and not the underlying reasons for the
disease.
If you suffer from any of these
digestive problems or diseases, I am a health coach and a nutritional
consultant with an advanced degree in nutritional biochemistry. If you would
like to schedule an appointment by Skype or in the person (in the Minneapolis
area), please email me at marissa.reeder53@gmail.com.
We can tailor a diet and supplement schedule tailored to your individual
symptoms and food preferences and create increased health and vitality in your
body!
Recommended reading:
http://chriskresser.com/a-healthy-gut-is-the-hidden-key-to-weight-loss
http://chriskresser.com/are-you-at-risk-for-diabetes-and-obesity
http://www.gapsdiet.com/
http://terrywahls.com/tag/intestinal-bacteria/
Recommended reading:
http://chriskresser.com/a-healthy-gut-is-the-hidden-key-to-weight-loss
http://chriskresser.com/are-you-at-risk-for-diabetes-and-obesity
http://www.gapsdiet.com/
http://terrywahls.com/tag/intestinal-bacteria/